What Is Sickle Cell Disease? - NHLBI, NIH
Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood cells are disc-shaped and flexible so they can move easily through the blood vessels.

Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH
Sickle cell disease is sometimes called sickle cell anemia. People have sickle cell trait if they inherit a copy of the sickle cell gene from one parent and a copy of the gene for normal hemoglobin, called hemoglobin A, from the other.

Sickle Cell Disease - Symptoms | NHLBI, NIH
Sickle Cell Disease Fact Sheet Learn basics about sickle cell disease, including symptoms, how to prevent health problems and treatment options.

Sickle Cell Disease - Treatment | NHLBI, NIH
Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments. Bone marrow transplants and gene therapies are potential cures for some people.

Sickle Cell Disease - Sickle Cell Trait | NHLBI, NIH
Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent, and a normal hemoglobin gene from the other parent. People who have sickle cell trait are sometimes called carriers . Sickle cell trait is different from sickle cell disease.

Evidence-Based Management of Sickle Cell Disease: Expert Panel Report ...
The purpose of these guidelines is to help people living with sickle cell disease (SCD) receive appropriate care by providing the best science-based recommendations to guide practice decisions. The target audience is primary care providers and other clinicians, nurses, and staff who provide emergency or continuity care to individuals with SCD.

Enfermedad de Células Falciformes (Sickle cell disease)
Enfermedad de Células Falciformes (Sickle cell disease) Overview La enfermedad de células falciformes (ECF) es el trastorno sanguíneo hereditario más común en los Estados Unidos. En esta hoja informativa, aprenda sobre las causas, los signos y síntomas, el diagnóstico y el tratamiento de la ECF.

Living With Sickle Cell Disease - NHLBI, NIH
Living with sickle cell disease involves receiving routine follow-up care, learning to manage a pain crisis, adopting a healthy lifestyle, and preventing health problems for yourself or your child.

September is National Sickle Cell Awareness Month - NHLBI, NIH
Other Sickle Cell Disease Resources Understanding sickle cell disease — Learn more about sickle cell disease, including symptoms, treatments, and lifestyle tips. Cure Sickle Cell Initiative — See how NHLBI-led research is paving the way for sickle cell disease cures.

Sickle Cell Genetics and Pathophysiology - NHLBI, NIH
Sickle Cell Genetics and Pathophysiology Research in the Laboratory of Sickle Cell Genetics and Pathophysiology, led by Dr. Swee Lay Thein, examines the genetic and biological factors underlying the phenotypic variability of sickle cell disease to accelerate translation of basic discovery to therapeutics.